Catalysis and Organic Synthesis Laboratory

Publications

2024 | 2023 | 2022 | 2021 |  2020 | 2019 |  2018 |  2017 | 2016 |  2015 | 2014 |  2013 |  2012 |  2011 |  2010 |  2009 |  2008 – 2000 | Patents

2010

  • 50. Mechanistic Dichotomy with Alkynes in the Formal Hydrohydrazination/Fischer Indolization Tandem Catalyzed by Ph3PAuNTf2/pTSA Binary Catalytic System

Nitin T. Patil* and Ashok Konala

📝 Eur. J. Org. Chem., 2010, 35, 6831 – 6839

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  • 49. Metal-Catalyzed Intramolecular Heteroatom (X) to Carbon (C) Functional Group Migration Reactions Involving Addition of X-Y Bonds Across Alkynes

Nitin T. Patil*, Rahul D. Kavthe and Yoshinori Yamamoto*

📝 Advances in Heterocyclic Chemistry, 2010, 101, 75 – 95

 

  • 48. Gold(I)-Catalyzed One-pot Reactions Between 2-Aminophenyl Alkynes and Alkynols Leading to the Formation of C-3 Substituted Indoles: A Case of Formal Carboamination of Alkynes

Nitin T. Patil*, Vipender Singh, Ashok Konala and Anil Kumar Mutyala

📝 Tetrahedron Lett., 2010, 51, 1493 – 1496

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  • 47. Au(I)-Catalyzed Direct Hydroamination-Hydroarylation and Double Hydroamination Reactions of Terminal Alkynes

Nitin T. Patil*, P. G. V. V. Lakshmi and Vipender Singh

📝 Eur. J. Org. Chem., 2010, 4719 – 4731

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  • 46. Facile Assembly of Fused Isoquinolines by Gold(I)-Catalyzed Coupling–Cyclization Reactions between o-Alkynylbenzaldehydes and Aromatic Amines Containing Tethered Nucleophiles

Nitin T. Patil*, Anil Kumar Mutyala, P. G. V. V. Lakshmi, P. V. K. Raju and Balasubramanian Sridhar

📝 Eur. J. Org. Chem., 2010, 1999 – 2007

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  • 45. Cooperative Catalysis with Metal and Secondary Amine: Efficient Synthesis of 2-Substituted Quinolines via Cascade Addition/Cycloisomerization Approach

Nitin T. Patil* and Vivek Raut

📝 J. Org. Chem., 2010, 75, 6961 – 6964

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  • 44. Au(I)-Catalyzed Cascade Reaction Involving Formal Double Hydroamination of Alkynes Bearing Tethered Carboxylic Groups: An Easy Access to Fused Dihydrobenzimidazoles and Tetrahydroquinazolines

Nitin T. Patil*, Anil Kumar Mutyala, P. G. V. V. Lakshmi, B. Gajula, Balasubramanian Sridhar, G. Potireddygari and Tadikamalla P. Rao

📝 J. Org. Chem., 2010, 75, 5963 – 5975

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  • 43. Pt(IV)-catalyzed Hydroamination-Triggered Cyclization: A Strategy to Fused Pyrrolo[1,2-a]quinoxalines, Indolo[1,2-a]quinoxalines and Indolo[3,2-c]quinolines

Nitin T. Patil*, Rahul D. Kavthe, Valmik S. Shinde and Balasubramanian Sridhar

📝 J. Org. Chem., 2010, 75, 3371 – 3380

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  • 42. Gold- and Platinum-Catalyzed Formal Markownikoff's Double Hydroamination of Alkynes: A Rapid Access to trahydroquinazolinones and Angularly-Fused Analogues

Nitin T. Patil*, Rahul D. Kavthe, Vivek S. Raut, Valmik S. Shinde and Balasubramanian Sridhar

📝 J. Org. Chem., 2010, 75, 1277 – 1280

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2009

  • 41. Alkyne Activation with Brønsted acids, iodine or gold complexes, and Its Fate Leading to Synthetic Application

Yoshinori Yamamoto*, Ilya D. Gridnev, Nitin T. Patil and  Tienan Jin

📝 Chem. Commun., 2009, 45, 5075 – 5087

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  • 40. Thorpe-Ingold Effect in Copper(II)-catalyzed Formal Hydroalkoxylation-Hydroarylation Reaction of Alkynols with Indoles

 Nitin T. Patil*, Vivek S. Raut, Rahul D. Kavthe, Vaddu V. N. Reddy and P. V. K. Raju

📝 Tetrahedron Lett., 2009, 50, 6576 – 6579

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  • 39. Highly Selective Electrophile-Induced Cascade Reactions between o-Alkynylbenzaldehydes and Styrene Oxides Leading to the Formation of 1-Naphthyl Ketones

Nitin T. Patil*, Ashok Konala, Vipender Singh and Vaddu V. N. Reddy

📝 Eur. J. Org. Chem., 2009, 5178 – 5184

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  • 38. Transition Metal-Catalyzed Cyclization Reactions of Functionalized Alkenes, Alkynes, and Allenes, Handbook of Cyclization Reactions

Nitin T. Patil* and Yoshinori Yamamoto*

📝 Wiley-VCH: Weinheim, Chapter 10, (2009)

 

  • 37. Platinum-catalyzed Formal Markownikoff's- hydroamination/Hydroarylation Cascade of Terminal Alkynes Assisted by Tethered Hydroxyl Groups

Nitin T. Patil*, Rahul D. Kavthe, Vivek S. Raut and Vaddu V. N. Reddy

📝 J. Org. Chem., 2009, 74, 6315 – 6318

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2008 - 2000 (Mentored Publications)

  1. Iodine-Mediated Electrophilic Cyclization of 2-Alkynyl-1-methylene Azide Aromatics Leading to Highly Substituted Isoquinolines and its Application to the Synthesis of Norchelerythrine
    Dirk Fischer, Hisamitsu Tomeba, Nirmal K. Pahadi, Nitin T. Patil, Zhibao Huo, Yoshinori Yamamoto. J. Am. Chem. Soc., 2008, 130, 15720 – 15725.

  2. Coinage Metal-Assisted Synthesis of Heterocycles
    Nitin T. Patil, Yoshinori Yamamoto. Chem. Rev., 2008, 108, 3395 – 3442.

  3. Synthesis of 1,3,4-Trisubstituted Isoquinolines by Iodine-Mediated Electrophilic Cyclization of 2-Alkynyl Benzyl Azides
    Dirk Fischer, Hisamitsu Tomeba, Nirmal K. Pahadi, Nitin T. Patil, Yoshinori Yamamoto. Angew. Chem., Int. Ed., 2007, 46, 4764 – 4766.

  4. Suppression of β-Hydride Elimination in the Intramolecular Hydrocarboxylation of Alkynes Leading to the Formation of Lactones
    Zhibao Huo, Nitin T. Patil, Tienan Jin, Nirmal K. Pahadi, Yoshinori Yamamoto. Adv. Synth. Catal., 2007, 349, 680 – 684.

  5. A Route to 2-Substituted Tetrahydroquinolines via Palladium-Catalyzed Intramolecular Hydroamination of Anilino-alkynes
    Nitin T. Patil, Huanyou Wu, Yoshinori Yamamoto. Tetrahedron, 2007, 63, 5954 – 5961 .

  6. Palladium Catalyzed Three Component Coupling Reactions Between Chromones, Alcohols, and Allylic Acetates: Diversity-Oriented Synthesis of Highly Substituted Chromones
    Nitin T. Patil, Huanyou Wu, Yoshinori Yamamoto. J. Org. Chem., 2007, 72, 6577 – 6579.

  7. Palladium-Catalyzed Cascade Reactions of Highly Activated Olefins
    Nitin T. Patil, Yoshinori Yamamoto. Synlett, 2007, 72, 1994 – 2005.

  8. Metal-Mediated Synthesis of Furans and Pyrroles
    Nitin T. Patil, Yoshinori Yamamoto. Arkivoc, 2007, 72, 121 – 141.

  9. Gold-Catalyzed Reactions of Oxo-alkynes
    Nitin T. Patil, Yoshinori Yamamoto. Arkivoc, 2007, 72, 6 – 19.

  10. Palladium-Catalyzed Allylation of Pronucleophiles with Alkynes at 50 °C – Remarkable Effect of 2-(Dicyclohexylphosphanyl)-2′-(dimethylamino)biphenyl as Ligand
    Nitin T. Patil, Dschun Song, Yoshinori Yamamoto. J. Org. Chem., 2006, 2006, 4211 – 4213.

  11. Gold Catalyzed Intramolecular Hydroamination of Allenes: A Case of Chirality Transfer
    Nitin T. Patil, Léopold Mpaka Lutete, Naoko Nishina, Yoshinori Yamamoto. Tetrahedron Lett., 2006, 47, 4749 – 4751.

  12. Allyltributylstannane: An Update
    Nitin T. Patil, Yoshinori Yamamoto. Tetrahedron Lett., 2006, 47, 4749 – 4751.

  13. Umpolung of π-Allylpalladium Complexes
    Nitin T. Patil, Yoshinori Yamamoto. J. J. Chem., 2006, 1, 13 – 23.

  14. Palladium Catalyzed Cascade Reactions Involving π-Allyl Palladium Chemistry
    Nitin T. Patil, Yoshinori Yamamoto. Topics in Organometallic Chemistry 2006, 19, 91 – 113.

  15. Palladium-Catalyzed Decarboxylative Aza-Michael Addition-Allylation Reactions between Allyl Carbamates and Activated Olefins. Generation of Quaternary Carbon Adjacent to Secondary Amine Carbon Center
    Nitin T. Patil, Zhibao Huo, Yoshinori Yamamoto. J. Org. Chem., 2006, 71, 6991 – 6995.

  16. Palladium-Catalyzed Intramolecular Asymmetric Hydroamination, Hydroalkoxylation and Hydrocarbonation of Alkynes
    Nitin T. Patil, Léopold Mpaka Lutete, Huanyou Wu, Nirmal K. Pahadi, Ilya D. Gridnev, Yoshinori Yamamoto. J. Org. Chem., 2006, 71, 4270 – 4279.

  17. Lactam Synthesis via Intramolecular Hydroamidation of Alkynes Catalyzed by Palladium Complexes
    Nitin T. Patil, Zhibao Huo, Gan B. Bajracharya, Yoshinori Yamamoto. J. Org. Chem., 2006, 71, 3612 – 3614.

  18. β-Alkyl-α-allylation of Michael Acceptors through the Palladium Catalyzed Three Component Coupling between Allylic Substrates, Trialkylboranes and Activated Olefins
    Nitin T. Patil, Zhibao Huo, Yoshinori Yamamoto. J. Org. Chem., 2006, 71, 2503 – 2506.

  19. Silver (I) Catalyzed Novel Cascade Cyclization Reactions: Incorporation of Allenes into the Isochromenes
    Nitin T. Patil, Nirmal K. Pahadi, Yoshinori Yamamoto. J. Org. Chem., 2005, 70, 10096 – 10098.

  20. Cu(I) Catalyst in DMF: An Efficient Catalytic System for the Synthesis of Furans from 2-(1-Alkynyl)-2-alken-1-ones
    Nitin T. Patil, Huanyou Wu, Yoshinori Yamamoto. J. Org. Chem., 2005, 70, 4531 – 4534.

  21. Progress in the Total Synthesis of Laurencin and Prelaureatin
    Nitin T. Patil, Yoshinori Yamamoto. Rec. Res. Develop. Org. Chem., 2005, 9, 131 – 146.

  22. A Novel Route to the Synthesis of Indolizidine (–)-209D: Excellent Diastereoselectivity in the Intramolecular Hydroamination of Alkynes
    Nitin T. Patil, Nirmal K. Pahadi, Yoshinori Yamamoto. Tetrahedron Lett., 2005, 46, 2101 – 2103.

  23. Pd(0)/PhCOOH Catalyzed Addition of O-Nucleophiles to Allenes and Internal Alkynes
    Nitin T. Patil, Nirmal K. Pahadi, Yoshinori Yamamoto. Can. J. Chem., 2005, 83, 569 – 573.

  24. A Convenient and Efficient Route for the Allylation of Aromatic Amines and α-Aryl Aldehydes with Alkynes in the Presence of a Pd(0)/PhCOOH Combined Catalyst System
    Nitin T. Patil, Huanyou Wu, Isao Kadota, Yoshinori Yamamoto. J. Org. Chem., 2004, 69, 8745 – 8750.

  25. Formation of a Quaternary Carbon Center through the Pd(0)/PhCOOH Catalyzed Allylation of Cyclic β-Keto Esters and 1,3-Diketones with Alkynes
    Nitin T. Patil, Yoshinori Yamamoto. J. Org. Chem., 2004, 69, 6478 – 6481.

  26. Synthesis of Cyclic Alkenyl Ethers via Intramolecular Cyclization of O-Alkynylbenzaldehydes. Importance of Combination between CuI Catalyst and DMF
    Nitin T. Patil, Yoshinori Yamamoto. J. Org. Chem., 2004, 69, 5139 – 5142.

  27. Microwave-Enhanced Pd(0)/Acetic Acid Catalyzed Allylation Reactions of C, Nand O-Pronucleophiles with Alkynes
    Nitin T. Patil, F. Nawaz Khan, Yoshinori Yamamoto. Tetrahedron Lett., 2004, 45, 8497 – 8499.

  28. Direct Allylic Substitution of Allyl Alcohols by Carbon Pronucleophiles in the Presence of a Palladium/CarboxylicAcid Catalyst under Neat Conditions
    Nitin T. Patil, Yoshinori Yamamoto. Tetrahedron Lett., 2004, 45, 3101 – 3103.

  29. Allylation of Carbon Pronucleophiles with Alkynes in the Presence of Palladium/Acetic Acid Catalyst
    Nitin T. Patil, Isao Kadota, Akinori Shibuya, Young Soo Gyoung, Yoshinori Yamamoto. Adv. Synth. Catal., 2004, 346, 800 – 804.

  30. An Improved Catalytic System, Pd(PPh3)4/PhCOOH Combined Catalyst, for the Allylation of Carbon Pronucleophiles with Allenes
    Nitin T. Patil, Nirmal K. Pahadi, Yoshinori Yamamoto. Synthesis, 2004, 12, 2186 – 2190.

  31. Enantioselective Catalytic Allylation of Carbonyl Groups by Umpolung of π-Allyl Palladium Complexes
    Nitin T. Patil, Yoshinori Yamamoto. Chemtracts, 2004, 17, 600 – 605.

  32. Concise and Practical Synthesis of (2S, 3R, 4R, 5R) and (2S, 3R, 4R, 5S)-1,6-Dideoxy-1,6-iminosugars
    Jayant N. Tilekar, Nitin T. Patil, Harishchandra S. Jadhav and Dilip D. Dhavale. Tetrahedron, 2003, 59, 1873 – 1876.

  33. 1-Aza-sugars from D-Glucose. Preparation of 1-Deoxy-5-(dehydroxymethyl) nojirimycin, its Analogues and Evaluation of Glycosidase Inhibitory Activity
    Nitin T. Patil, Sheeja John, Sushma G. Sabharwal and Dilip D. Dhavale. Bioorg. Med. Chem., 2003, 10, 2155 – 2160.

  34. A Short and Efficient Synthesis of 1-Deoxy-castanospermine and 1-Deoxy-8a-epi-castanospermine
    Nitin T. Patil, Jayant N. Tilekar and Dilip D. Dhavale. Tetrahedron Lett., 2001, 45, 747 – 749.

  35. Intermolecular Michael Addition of Substituted Amines to Sugar Derived α, β-Unsaturated Ester: Synthesis of 1-Deoxy-D-gluco- and L-ido-homonojirimycin, 1-Deoxy- castanospermine and 1-Deoxy-8a-epi-castanospermine
    Nitin T. Patil, Jayant N. Tilekar and Dilip D. Dhavale. J. Org. Chem., 2001, 66, 1065 – 1074.

  36. Synthesis of C1-C6 Segment of Carbonolide B: Wolf Rearrangement of Sugar α-Diazo Ketones
    Nitin T. Patil, Jayant N. Tilekar and Dilip D. Dhavale. Synthesis, 2000, 2000, 395 – 398.